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pentobarbital will lessen the extent or effect of atazanavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Unfamiliar.pentobarbital will lower the extent or result of darifenacin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.Watch Carefully (one)pentobarbital will minimize the level o